State-of-the-Art Plenary Sessions

​​​​Thursday, May 14, 2015

​ESPID Organised Plenary Session 1: Addressing the Needs of the Many: Vaccines to Prevent Colonization

08:30-09:15, Hall 1

Addressing the Needs of the Many: Vaccines to Prevent Colonization​

Richard Malley, US

ESPID Organised Plenary Session 2: Pediatric Vaccines Today and Tomorrow

09:15-10:00, Hall 1

Andrew Pollard, UK

Pediatric Vaccines Today and Tomorrow

Immunisation is the most important global programme for child health and continues to reduce mortality and morbidity in the first 5 years of life. There are major challenges today for maintaining the incredible impact of our immunisation programmes whether it is delivery of vaccines to remote villages in Africa, responding to the Ebola outbreak, closing the polio story, or maintaining confidence in measles vaccine to prevent outbreaks, such as the ongoing transmission across the US. While these are immense remaining challenges for the global heatlh providers and funders, immunisation has transformed our society and perhaps our greatest challenge today is about access and communication. The success of vaccines used thus far provides a strong argument for new vaccine development with the aim of further reducing morbidity and mortality. There important developments in vaccines for RSV, the leading cause of infant hospitalisation in industrialised countries and one of the leading causes of infant mortality globally. Vaccines for the primary cause of neonatal meningitis, group B streptococcus, are within sight and many vaccines with potential against nosocomial pathogens or for use in specific populations could be available in the decade ahead. One of the main issues that will be faced for many new vaccines, in the context of a limited health budget, are policy questions over the balance between spending on rare severe diseases and common mild diseases, which may have a similar financial burden for health services. Addressing and communicating the value of vaccines as tools for sustaining and improving child health has never been more pressing.

​​​Friday, May 15, 2015

ESPID Organised Plenary Lecture 3: Antimicrobial Resistance - All You Need to Know

17:00-17:45, Hall 1

Pentti Huovinen, Finlan​d

Mechanisms of Antimicrobial Resistance​

In a vote to determine the focus of a new research effort funded by the UK government, the British public named antibiotic resistance as one of the most pressing challenges of modern times. This level of knowledge is fruit of the continuous information dealt by the infectious diseases community.Indeed, antibacterial resistance has for decades been a growing threat to the effective treatment. Until know, practically all clinically important bacteria have developed resistance against majority of antibacterial compounds. Countless amounts of resistance mechanisms have been identified.The clinicians need knowledge of bacterial resistance mechanisms in planning the most effective treatment options. Without studying the resistance mechanisms, surveillance of resistant bacteria is not well understood. In addition, mechanisms behind resistance have also to be known to find best ways to tackle spread of resistant bacteria. Lord Kelvin said wisely: “If you cannot measure it, you cannot improve it.” In the second week of this year 2015, Nature published an article of a new antibiotic teixobactin. The authors conclude: “The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance.” I have heard this sentence several times in 1970’ies and again in 1980’ies. Is there finally light in the tunnel?  ​

ESPID Organised Plenary Lecture 4: Antimicrobial Resistance - All You Need to Know

17:45-18:30, Hall 1

Jan Kluytmans, The Netherlands

Prevention of Antimicrobial Resistance in the Clinic

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